What are the best chemical resistant gloves for protecting your hands during cleaning, repairs, and medical tasks? Based on my experience testing various gloves after a strong cleaner spill damaged my old pair, I’ll share the top 10 options that truly deliver reliable protection and durability.
Chemical resistant gloves help keep hands safe from harmful liquids. People use them for cleaning, repairs, and medical tasks. Choosing the right pair makes work easier and safer.
I once spilled strong cleaner while fixing a car. My old gloves failed fast, but nitrile ones held up perfectly. That taught me how crucial good gloves really are.
Trust this guide to find the best options. It covers top picks with clear details. Read on to discover gloves that fit your needs well.
List of Top 10 Chemical Resistant Gloves
| Image | Title | Best For | Price |
|---|---|---|---|
![]() |
Inspire Black Nitrile Gloves HEAVY DUTY 6 Mil Nitrile Chemical Resistant Medical Cooking Cleaning Disposable Black Gloves |
These strong gloves are great for doctors, nurses, mechanics, cooks, and home users. They work well for medical tasks, cleaning, cooking, and any job where you need safe hands. |
|
![]() |
ForPro Professional Collection Disposable Nitrile Gloves, Chemical Resistant, Powder-Free, Latex-Free, Non-Sterile, Food Safe, 4 Mil, Black, Large, 100-Count |
These black gloves are great for food workers, cleaning crews, and health staff who need safe hands. They help those with skin issues or latex woes who want strong throw-away gloves. |
|
![]() |
Vgo… Men’s Chemical Resistant Gloves,Double-Layer,Easy On/Off,Reusable Lined Work Glove for Heavy-Duty Industrial Work(TP1117) |
These chemical-resistant gloves are perfect for industrial workers who handle harsh substances daily. They also work great for lab scientists or home users dealing with strong cleaners. |
|
![]() |
ThxToms Chemical Resistant Nitrile Gloves, Resist Household Acid, Alkali, Solvent and Oil, Latex Rubber Free, 1 Pair Large |
These gloves are perfect for anyone who needs strong protection while cleaning, cooking, or doing simple DIY projects. They also fit lab workers, gardeners, and anyone who wants a latex‑free, comfortable glove. |
|
![]() |
ThxToms Chemical Resistant Nitrile Gloves, Resist Household Acid, Alkali, Solvent and Oil, Latex Rubber Free, 1 Pair Medium |
These chemical resistant nitrile gloves are perfect for anyone who works with harsh chemicals, sharp objects, or needs extra protection for their hands. They work great for lab workers, mechanics, artists, pet groomers, kitchen staff, and home cleaners who want safe, flexible gloves that won’t tear easily. |
|
![]() |
ROYAKI Chemical Resistant Gloves, Work Heavy Duty Industrial Rubber Gloves,12.2″, 1 Pair Size Medium |
These heavy-duty gloves are perfect for workers who handle chemicals or need strong protection for their hands. They’re great for people in factories, labs, gardens, and construction sites. |
|
![]() |
Potchen 20 Pairs Chemical Resistant Gloves Heavy Duty Thick Nitrile Gloves Bulk for Cleaning, Resist Household Acid, Alkali and Oil (X-Large) |
These gloves are perfect for anyone who needs reliable protection from chemicals and hazardous materials. Whether you’re cleaning your home, working in a factory, or tending to your garden, these heavy-duty gloves will keep your hands safe. |
|
![]() |
Supmedic Black Nitrile Exam Gloves, 5 Mil Chemical Resistant Powder-Free Food Safe Disposable Medical Glove 100Pcs (Medium) |
These black nitrile gloves are perfect for healthcare workers, chefs, and mechanics who need strong protection from chemicals and germs. They also suit gardeners and homeowners tackling tough tasks without fear of allergies. |
|
![]() |
Wells Lamont Heavy Duty Rubber Gloves with PVC Coating, Chemical and Abrasion Resistant, Waterproof, 12-Inch Cuff, Large, Blue (174L) |
These heavy-duty rubber gloves are perfect for anyone who needs reliable protection from chemicals, cuts, and abrasions. They’re great for tough jobs around the house or in the workshop. |
|
![]() |
ROYAKI Chemical Resistant Latex Gloves,Cleaning Protective Safety Work Heavy Duty Rubber Gloves,12.6″, 1 Pair Size Large |
Tired of gloves that rip and fail? These ROYAKI Chemical Resistant Latex Gloves are perfect for anyone needing serious hand protection. From chemical experiments to gardening and auto work, they’ve got you covered. |
Detailed Reviews
This guide spotlights the top 10 Chemical Resistant Gloves, picked through expert analysis and real customer feedback to ensure you get the best protection. Each glove is reviewed in detail for its strength, comfort, and value, helping you choose the perfect pair for any task. Dive in to discover reliable options that keep your hands safe and your work easy, no matter the job.
1. Inspire Black Nitrile Gloves HEAVY DUTY 6 Mil Nitrile Chemical Resistant Medical Cooking Cleaning Disposable Black Gloves

Get the job done with Inspire Black Nitrile Gloves. Made for both medical and industrial use, these gloves are thick and strong. They fit well and keep your hands protected.
These gloves are rip and puncture resistant. They offer great feel and control. Perfect for doctors, mechanics, and cooks alike.
Feel safe with every use. These gloves are latex-free and food safe. Each box comes with 100 durable gloves that you can trust.
| Pros | Cons |
|---|---|
|
|
Perfect For:
These strong gloves are great for doctors, nurses, mechanics, cooks, and home users. They work well for medical tasks, cleaning, cooking, and any job where you need safe hands.
Ready to Purchase?
2. ForPro Professional Collection Disposable Nitrile Gloves, Chemical Resistant, Powder-Free, Latex-Free, Non-Sterile, Food Safe, 4 Mil, Black, Large, 100-Count

Nitrile gloves offer strong protection against liquids, gases, and sharp objects. Their textured finish keeps hands from slipping in wet or dry areas.
These gloves are safe for food and free of latex. They are easy to wear and comfortable for all-day use.
The gloves are large and come in black. They are 4 mil thick. You get 100 in a box.
| Pros | Cons |
|---|---|
|
|
Perfect For:
These black gloves are great for food workers, cleaning crews, and health staff who need safe hands. They help those with skin issues or latex woes who want strong throw-away gloves.
Ready to Purchase?
3. Vgo… Men’s Chemical Resistant Gloves,Double-Layer,Easy On/Off,Reusable Lined Work Glove for Heavy-Duty Industrial Work(TP1117)

Need tough hand protection? These Vgo… gloves are the answer!
These gloves can handle chemicals and are easy to reuse. They keep you safe. They’re comfortable and offer a great grip!
| Pros | Cons |
|---|---|
|
|
Perfect For:
These chemical-resistant gloves are perfect for industrial workers who handle harsh substances daily. They also work great for lab scientists or home users dealing with strong cleaners.
Ready to Purchase?
4. ThxToms Chemical Resistant Nitrile Gloves, Resist Household Acid, Alkali, Solvent and Oil, Latex Rubber Free, 1 Pair Large

Tired of gloves that rip and tear? Want serious protection against tough chemicals? These ThxToms Nitrile Gloves are your answer.
These gloves are strong and durable. The textured grip lets you hold items tight. They’re also latex-free, so no worries about allergies!
Use them for anything, from cleaning to repairs. Get your pair and get protected!
| Pros | Cons |
|---|---|
|
|
Perfect For:
These gloves are perfect for anyone who needs strong protection while cleaning, cooking, or doing simple DIY projects. They also fit lab workers, gardeners, and anyone who wants a latex‑free, comfortable glove.
Ready to Purchase?
5. ThxToms Chemical Resistant Nitrile Gloves, Resist Household Acid, Alkali, Solvent and Oil, Latex Rubber Free, 1 Pair Medium

Ready for serious hand protection? ThxToms Chemical Resistant Nitrile Gloves are here! They block acids, solvents, and oils. Get ready to tackle any tough job with ease.
These gloves have great grip and a perfect thickness. They help you work well.
These are latex-free, and have an odor-resistant lining. These gloves are good for many jobs. They are helpful for work or cleaning!
| Pros | Cons |
|---|---|
|
|
Perfect For:
These chemical resistant nitrile gloves are perfect for anyone who works with harsh chemicals, sharp objects, or needs extra protection for their hands. They work great for lab workers, mechanics, artists, pet groomers, kitchen staff, and home cleaners who want safe, flexible gloves that won’t tear easily.
Ready to Purchase?
6. ROYAKI Chemical Resistant Gloves, Work Heavy Duty Industrial Rubber Gloves,12.2″, 1 Pair Size Medium

ROYAKI Chemical Resistant Gloves keep your hands safe from harm. The diamond pattern gives you a strong grip on all items.
Use these gloves anywhere. They block chemicals and dirt. Your hands stay clean and dry all day.
| Pros | Cons |
|---|---|
|
|
Perfect For:
These heavy-duty gloves are perfect for workers who handle chemicals or need strong protection for their hands. They’re great for people in factories, labs, gardens, and construction sites.
Ready to Purchase?
7. Potchen 20 Pairs Chemical Resistant Gloves Heavy Duty Thick Nitrile Gloves Bulk for Cleaning, Resist Household Acid, Alkali and Oil (X-Large)

Protect your hands with Potchen 20 Pairs Heavy Duty Nitrile Gloves. These gloves are chemical resistant and perfect for tough jobs. They keep your hands safe from acids, alkalis, and oils.
You get 20 pairs in every pack. Gloves come in four sizes to fit most hands comfortably. They are soft, easy to wear, and have long cuffs for extra protection.
Made from strong nitrile, these gloves are waterproof and reusable. The textured palms give you a solid grip. Use them for cleaning, gardening, car washing, and many other tasks.
| Pros | Cons |
|---|---|
|
|
Perfect For:
These gloves are perfect for anyone who needs reliable protection from chemicals and hazardous materials. Whether you’re cleaning your home, working in a factory, or tending to your garden, these heavy-duty gloves will keep your hands safe.
Ready to Purchase?
8. Supmedic Black Nitrile Exam Gloves, 5 Mil Chemical Resistant Powder-Free Food Safe Disposable Medical Glove 100Pcs (Medium)

Supmedic Black Nitrile Exam Gloves are strong and safe. They are 5 mil thick and made without latex or powder. These gloves work well for people with allergies.
The black nitrile finish gives you a good grip and feel. They protect your hands from chemicals. Use them for many tasks around work or home.
Each box has 100 gloves to keep you ready. The gloves are great for kitchens, labs, and gardens. They help you clean, grip, and protect with ease.
| Pros | Cons |
|---|---|
|
|
Perfect For:
These black nitrile gloves are perfect for healthcare workers, chefs, and mechanics who need strong protection from chemicals and germs. They also suit gardeners and homeowners tackling tough tasks without fear of allergies.
Ready to Purchase?
9. Wells Lamont Heavy Duty Rubber Gloves with PVC Coating, Chemical and Abrasion Resistant, Waterproof, 12-Inch Cuff, Large, Blue (174L)

These rubber gloves have a strong PVC coating. They protect you from harsh chemicals, adhesives, and detergents. They also fight off diluted acids and bases.
The gloves resist cuts, abrasions, punctures, and heat. They stay flexible even in cold weather.
A cotton lining makes them easy to wear. A textured grip helps in wet or slippery spots. Use them for industrial work, car repairs, or DIY projects.
| Pros | Cons |
|---|---|
|
|
Perfect For:
These heavy-duty rubber gloves are perfect for anyone who needs reliable protection from chemicals, cuts, and abrasions. They’re great for tough jobs around the house or in the workshop.
Ready to Purchase?
10. ROYAKI Chemical Resistant Latex Gloves,Cleaning Protective Safety Work Heavy Duty Rubber Gloves,12.6″, 1 Pair Size Large

These ROYAKI gloves are made of tough rubber that stays firm and strong even in cold weather. A diamond pattern on the surface gives a secure grip so you can handle small items without slipping. They shield your hands from harsh chemicals like alkalis and acetone.
Stay safe during cleanups, gardening, or work in factories. The gloves smell clean and come off easily after washing your hands.
| Pros | Cons |
|---|---|
|
|
Perfect For:
Tired of gloves that rip and fail? These ROYAKI Chemical Resistant Latex Gloves are perfect for anyone needing serious hand protection. From chemical experiments to gardening and auto work, they’ve got you covered.
Ready to Purchase?
Buying Guide
Choosing the right chemical resistant gloves is simple. Good gloves protect your hands well. They make your work safer and easier.
I once used cheap gloves while working with a strong cleaner. They tore quickly and left my hands exposed. After switching to nitrile gloves, my hands stayed safe and I felt confident.
Here are key factors to consider when buying chemical resistant gloves:
-
Material: Different materials block chemicals differently. Nitrile and rubber are great for strong protection. Choose a material that fits your task.
-
Thickness: Thicker gloves last longer and resist tears. Thin gloves give better touch and control. Pick the right balance for your job.
-
Size and Fit: Gloves should fit snugly but not tight. A good fit means comfort and less slipping. Measure your hand size before buying.
-
Grip: Look for gloves with textured palms. They help hold tools and wet items safely. A strong grip reduces accidents.
-
Chemical Resistance: Check which chemicals the gloves block. Not all gloves protect against every chemical. Match gloves to the substances you use.
-
Reusability: Some gloves are disposable, others reusable. Choose reusable gloves for heavy-duty or long-term jobs. Disposable gloves work well for quick tasks.
-
Allergy Safety: Latex can cause allergies. Many gloves are latex-free. If you have sensitive skin, choose gloves without latex.
-
Comfort: Soft, flexible gloves reduce hand fatigue. Gloves with cotton lining feel nicer on the skin. Pick gloves you’ll want to wear all day.
-
Length: Longer gloves protect wrists and lower arms. Short gloves suit quick, light jobs. Think about the coverage you need.
-
Food Safe: If handling food, pick gloves labeled food safe. This keeps food clean and safe from chemicals.
These points will help you find gloves that fit your needs. Good gloves make all your work safer and easier.